Consultant Physician in Infectious Diseases

Research Interests:

Infection in Immunocompromised Hosts
Transplant Infectious Diseases
Bloodborne Virus Infection (HIV/Viral Hepatitis)


Dáire O’Shea is a Consultant Physician in Infectious Diseases in Edinburgh and an Honorary Clinical Senior Lecturer with University of Edinburgh. He is a graduate of Trinity College Dublin Medical School, and undertook Internal Medicine and Specialist Infectious Diseases Training in Ireland following by a Transplant Infectious Diseases Fellowship with the Alberta Transplant Institute in Canada.  He was appointed to the ID Academic Faculty of the University of Alberta in 2013, prior to taking up his current position in 2014. Subspecialist interests include infection in immunocompromised hosts, in particular Transplant Infectious Diseases, and bloodborne virus infection (viral hepatitis/HIV). Research interests focus on immunopathogenesis and immune determinants of infection outcomes.

Key Publications:


Expect the unexpected – Implications for next phase of COVID-19 response. Clifford S, Cevik M, Campbell R, O’Shea D, Sutherland RK. Infect Prev Pract 2021 Jun;3(2):100118. doi: 10.1016/j.infpip.2021.100118.


The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections. Egli A, Santer DM, O’Shea D, Tyrrell D, Houghton M Emerg Microbes Infect. 2014 Jul; 3(7): e51.

IL-28B is a key regulator of B- and T-cell vaccine responses against influenza. Egli A, Santer DM, O’Shea D, Barakat K, …, Kumar D PLoS Pathog 2014 Dec 11;10(12):e1004556.


Life-Threatening Infection in Transplant Recipients. O’Shea DT , Humar A. Crit Care Clin 2013 Oct;29(4):953-73