Position:

Clinical Director RIDU, Consultant Infectious Disease Physician, Honorary Senior Lecturer University of Edinburgh

Research Interests:

Health Equity
Infectious Diseases

Projects/ grants:

COVID-19 DataLoch collaboration investigating impact of deprivation

Key Publications:

2020

Coronavirus disease (COVID-19) Community Testing Team in Scotland: A 14-day review, 6 to 20 February 2020. Mark K, Steel K, Stevenson J, Evans C, McCormick D, Willocks L, McCallum A, Jones L, Johannessen I, Templeton K, Koch OMackintosh C. Euro Surveill.2020 Mar;25(12):2000217. doi: 10.2807/1560-7917.ES.2020.25.12.2000217.

Inequitable access to an outpatient parenteral antimicrobial therapy service: linked cross-sectional study. Sumpter C, Russell CD, Mackintosh C. Int J Equity Health. 2020 Sep 1;19(1):150. doi: 10.1186/s12939-020-01261-w.

2011

Outpatient parenteral antibiotic therapy (OPAT) for bone and joint infections: experience from a UK teaching hospital-based service. Mackintosh CL, White HA, Seaton RA. J Antimicrob Chemother. 2011 Feb;66(2):408-15. doi: 10.1093/jac/dkq445.

2008

Failure to respond to the surface of Plasmodium falciparum infected erythrocytes predicts susceptibility to clinical malaria amongst African children. Mackintosh CL, Mwangi T, Kinyanjui SM, Mosobo M, Pinches R, Williams TN, Newbold CI, Marsh K. Int J Parasitol. 2008 Oct;38(12):1445-54. doi: 10.1016/j.ijpara.2008.03.009

All Publications:

2021

Equity for excellence in academic institutions: a manifesto for change. Wedekind L, Noe A, Mokaya J, Tamandjou C, Kapulu M,…Mackintosh CL,… Matthews PC. Wellcome Open Research 2021, 6:142

Diagnostic performance of the combined nasal and throat swab in patients admitted to hospital with suspected COVID-19. Lee KK, Doudesis D, Ross DA, Bularga A, MacKintosh CL, Koch O, Johannessen I, Templeton K, Jenks S, Chapman AR, Shah ASV, Anand A, Perry MR, Mills NL; DataLoch COVID-19 Collaboration. BMC Infect Dis. 2021 Apr 6;21(1):318. doi: 10.1186/s12879-021-05976-1.

As Part of the RECOVERY Collaborative Group:

Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. RECOVERY Collaborative Group. Lancet. 2021 Feb 13;397(10274):605-612. doi: 10.1016/S0140-6736(21)00149-5

Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. RECOVERY Collaborative Group. Lancet. 2021 May 1;397(10285):1637-1645. doi: 10.1016/S0140-6736(21)00676-0.

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial. RECOVERY Collaborative Group. Lancet. 2021 May 29;397(10289):2049-2059. doi: 10.1016/S0140-6736(21)00897-7.

2020

The index case of SARS-CoV-2 in Scotland. Hill KJ, Russell CD, Clifford S, Templeton K, Mackintosh CL, Koch O, Sutherland RK. J Infect. 2020 Jul;81(1):147-178. doi: 10.1016/j.jinf.2020.03.022.

Drive-through testing in COVID-19: experience from NHS Lothian. Hill K, Campbell R, Mutch C, Koch O, Mackintosh C. Clin Med (Lond). 2020 May;20(3):290-291. doi: 10.7861/clinmed.2020-0160

Coronavirus disease (COVID-19) Community Testing Team in Scotland: A 14-day review, 6 to 20 February 2020. Mark K, Steel K, Stevenson J, Evans C, McCormick D, Willocks L, McCallum A, Jones L, Johannessen I, Templeton K, Koch O, Mackintosh C. Euro Surveill. 2020 Mar;25(12):2000217. doi:10.2807/1560-7917.ES.2020.25.12.2000217

Inequitable access to an outpatient parenteral antimicrobial therapy service: linked cross-sectional study. Sumpter C, Russell CD, Mackintosh C. Int J Equity Health. 2020 Sep 1;19(1):150. doi: 10.1186/s12939-020-01261-w.

A Subgroup of Patients With Hospital-acquired Pneumonia Do Not Require Broad-spectrum Gram-negative Antimicrobial Coverage. Russell CD, Whittaker E, Dee DP, Farquhar E, Saenz de Villaverde A, Evans MH, Laurenson IF, Mackintosh CL, Cevik M. Clin Infect Dis. 2020 Dec 17;71(10):e710-e713. doi: 10.1093/cid/ciaa391.

2019

Tractable targets for meropenem-sparing antimicrobial stewardship interventions. Clark D Russell, Ian F Laurenson, Morgan H Evans, Claire L Mackintosh. JAC-Antimicrobial Resistance, Volume 1, Issue 2, September 2019, dlz042, https://doi.org/10.1093/jacamr/dlz042

A pilot experience of common European infectious diseases curriculum for medical students: the IDEAL summer school. Charlier C, Wolf FI, Vlieghe E, Planquette B, Damme PV, Gaetano K, Buffet P, Henry B, Cevik M, Leen C, Laurenson I, Cameron H, Ogavu J, Nabankema E, Omona V, Valnaud P, Mackintosh C, Johannessen I, Geertruyden JV, Jeunne CL, Cauda R. Future Microbiol. 2019 Mar;14:369-372. doi: 10.2217/fmb-2019-0037

2018

Staphylococcus aureus endocarditis associated with injecting new psychoactive substances. Joshi SS, Henderson N, Griffith DJ, Henriksen PA, Denvir MA, Macsween KF, Mackintosh CL, Inverarity D. J R Coll Physicians Edinb. 2018 Dec;48(4):304-310. doi: 10.4997/JRCPE.2018.404.

2017

International infectious diseases teaching to undergraduate medical students: A successful European collaborative experience. Charlier C, Johannessen I, Mackintosh CL, Wilks D, Med Teach. 2017 Sep;39(9):981-986. doi: 10.1080/0142159X.2017.1332364.

2016

Diagnosis and features of hospital-acquired pneumonia: a retrospective cohort study. Russell CD, Koch O, Laurenson IF, O’Shea DT, Sutherland R, Mackintosh CL. J Hosp Infect. 2016 Mar;92(3):273-9. doi: 10.1016/j.jhin.2015.11.013.

Staphylococcus aureus bacteraemia associated with injected new psychoactive substances. Griffith DJ, Mackintosh CL, Inverarity D. Epidemiol Infect. 2016 Apr;144(6):1257-66. doi: 10.1017/S095026881500271X

2014

A granulomatous chronic disease. Stockdale AJ, Mackintosh CL, Roberston KE, Helgason KO. Am J Med. 2014 May;127(5):e5-6. doi: 10.1016/j.amjmed.2013.12.012

2013

Improving antimicrobial prescribing: implementation of an antimicrobial i.v.-to-oral switch policy. McCallum AD, Sutherland RK, Mackintosh CL. J R Coll Physicians Edinb. 2013;43(4):294-300. doi: 10.4997/JRCPE.2013.403.

2012

Targets of antibodies against Plasmodium falciparum-infected erythrocytes in malaria immunity. Chan JA, Howell KB, Reiling L, Ataide R, Mackintosh CL, Fowkes FJ, Petter M, Chesson JM, Langer C, Warimwe GM, Duffy MF, Rogerson SJ, Bull PC, Cowman AF, Marsh K, Beeson JG. J Clin Invest. 2012 Sep;122(9):3227-38. doi: 10.1172/JCI62182.

2011

Outpatient parenteral antibiotic therapy (OPAT) for bone and joint infections: experience from a UK teaching hospital-based service. Mackintosh CL, White HA, Seaton RA. J Antimicrob Chemother. 2011 Feb;66(2):408-15. doi: 10.1093/jac/dkq445

2010

Hospitalised adult patients with Suspected 2009 H1N1 Infection at Regional Infectious Diseases Units in Scotland–most had alternative final diagnoses. Ho A, Fox R, Seaton RA, MacConnachie A, Peters E, Mackintosh CL, Todd WT, Kennedy N, Dundas S, Gunson R. J Infect. 2010 Jan;60(1):83-5. doi: 10.1016/j.jinf.2009.11.001

2009

Analysis of immunity to febrile malaria in children that distinguishes immunity from lack of exposure. Bejon P, Warimwe G, Mackintosh CL, Mackinnon MJ, Kinyanjui SM, Musyoki JN, Bull PC, Marsh K. Infect Immun. 2009 May;77(5):1917-23. doi: 10.1128/IAI.01358-08

2008

Acquisition of naturally occurring antibody responses to recombinant protein domains of Plasmodium falciparum erythrocyte membrane protein 1. Mackintosh CL, Christodoulou Z, Mwangi TW, Kortok M, Pinches R, Williams TN, Marsh K, Newbold CI. Malar J. 2008 Aug 16;7:155. doi: 10.1186/1475-2875-7-155

Failure to respond to the surface of Plasmodium falciparum infected erythrocytes predicts susceptibility to clinical malaria amongst African children. Mackintosh CL, Mwangi T, Kinyanjui SM, Mosobo M, Pinches R, Williams TN, Newbold CI, Marsh K. Int J Parasitol. 2008 Oct;38(12):1445-54. doi: 10.1016/j.ijpara.2008.03.009

2004

Clinical features and pathogenesis of severe malaria. Mackintosh CL, Beeson JG, Marsh K. Trends Parasitol. 2004 Dec;20(12):597-603. doi: 10.1016/j.pt.2004.09.006.

1997

Elimination of motor nerve terminals in neonatal mice expressing a gene for slow wallerian degeneration (C57Bl/Wlds). Parson SH, Mackintosh CL, Ribchester RR. Eur J Neurosci. 1997 Aug;9(8):1586-92. doi: 10.1111/j.1460-9568.1997.tb01516.x.